LY 223592
LY 223592 (Compound I-a) is a Gemcitabine (HY-17026) derivative. LY 223592 has the biological activity of highly selective inhibition of lung cancer cell proliferation (IC50 = 5.6 nM in A549 cells) and low cytotoxicity to normal cells. LY 223592 can be used for the research of cancer, such as non-small cell lung cancer (NSCLC) [1].
Product Specifications
CAS Number
[103828-82-6]
UNSPSC
12352005
Target
Drug Derivative
Related Pathways
Others
Field of Research
Cancer
Smiles
FC1(F)[C@H](O)[C@@H](CO)O[C@H]1N2C3=C(C(N=C(N3)N)=O)N=C2
Molecular Formula
C10H11F2N5O4
Molecular Weight
303.22
References & Citations
[1]Tang Qian, et al. A kind of medicine for treating non-small cell lung cancer and preparation method thereof. CN110684062A. 2022-12-13
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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