P-SCN-Bn-DOTA (Standard)

P-SCN-Bn-DOTA (Standard) is the analytical standard of p-SCN-Bn-DOTA. This product is intended for research and analytical applications. p-SCN-Bn-DOTA is a bifunctional chelating agent. p-SCN-Bn-DOTA can simultaneously chelate radionuclides and link monoclonal antibody for radioimmunoresearch of tumor[1][2].

Product Specifications

CAS Number

[127985-74-4]

UNSPSC

12352100

Target

Others; Reference Standards

Related Pathways

Others

Field of Research

Cancer

Smiles

O=C(O)CN1C(CC2=CC=C(N=C=S)C=C2)CN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC1

Molecular Formula

C24H33N5O8S

Molecular Weight

551.61

References & Citations

[1]Vera DRB, et, al. Preclinical evaluation of (177) lu-nimotuzumab: a potential tool for radioimmunotherapy of epidermal growth factor receptor-overexpressing tumors. Cancer Biother Radiopharm. 2011 Jun;26 (3) :287-97.|[2]Giannini G, et, al. Synthesis and preliminary in vitro evaluation of DOTA-Tenatumomab conjugates for theranostic applications in tenascin expressing tumors. Bioorg Med Chem. 2019 Aug 1;27 (15) :3248-3253.