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L-161638

L-161638 is a potent, selective and orally active AT2 receptor antagonist. L-161638 can be used for the research of cardiovascular disease, such as hypertension[1].

Product Specifications

CAS Number

[150484-73-4]

UNSPSC

12352005

Target

Angiotensin Receptor

Related Pathways

GPCR/G Protein

Field of Research

Cardiovascular Disease

Smiles

O=C(C1=CC=CS1)N(C2=CC3=C(N=C(CC)N(CC4=CC=C(C5=CC=CC=C5C6=NNN=N6)C=C4)C3=O)C=C2)CC7=CC=CC=C7

Molecular Formula

C36H29N7O2S

Molecular Weight

623.73

References & Citations

[1]Tomasz W. Glinka, et al. L-161,638: A potent AT2 selective quinazolinone angiotensin II binding inhibitor, Bioorganic & Medicinal Chemistry Letters, Volume 4, Issue 12, 1994, Pages 1479-1484, ISSN 0960-894X

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

AT2 Receptor

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