L-161638
L-161638 is a potent, selective and orally active AT2 receptor antagonist. L-161638 can be used for the research of cardiovascular disease, such as hypertension[1].
Product Specifications
CAS Number
150484-73-4
UNSPSC
12352005
Target
Angiotensin Receptor
Related Pathways
GPCR/G Protein
Field of Research
Cardiovascular Disease
Smiles
O=C(C1=CC=CS1)N(C2=CC3=C(N=C(CC)N(CC4=CC=C(C5=CC=CC=C5C6=NNN=N6)C=C4)C3=O)C=C2)CC7=CC=CC=C7
Molecular Formula
C36H29N7O2S
Molecular Weight
623.73
References & Citations
[1]Tomasz W. Glinka, et al. L-161,638: A potent AT2 selective quinazolinone angiotensin II binding inhibitor, Bioorganic & Medicinal Chemistry Letters, Volume 4, Issue 12, 1994, Pages 1479-1484, ISSN 0960-894X
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
AT2 Receptor
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