L-163017
L-163017 is a potent, orally active and nonpeptide angiotensin II receptor (AT) antagonist. L-163017 can inhibit prevent the pressor response to angiotensin II and reduce blood pressure. L-163017 can be used for the research of cardiovascular disease, such as hypertension[1].
Product Specifications
CAS Number
[169281-98-5]
UNSPSC
12352005
Target
Angiotensin Receptor
Related Pathways
GPCR/G Protein
Field of Research
Cardiovascular Disease
Smiles
O=C(OCCC(C)C)NS(=O)(C1=CC=CC=C1C2=CC=C(CN3C(CCC)=NC4=C(C)C(NC(C5=CC=CC=C5)=O)=CN=C43)C=C2)=O
Molecular Formula
C36H39N5O5S
Molecular Weight
653.79
References & Citations
[1]Kivlighn SD, et al. In vivo pharmacology of an angiotensin AT1 receptor antagonist with balanced affinity for AT2 receptors. Eur J Pharmacol. 1995 Dec 29;294 (2-3) :439-50.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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