Oleylphosphocholine

Oleylphosphocholine is an orally active antifungal and antiparasitic agent. Oleylphosphocholine is promising for research of invasive fungal diseases (e.g., aspergillosis) and visceral leishmaniasis[1][2].

Product Specifications

CAS Number

[257925-44-3]

UNSPSC

12352211

Target

Fungal; Parasite

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Smiles

CCCCCCCCC/C=C\CCCCCCCOP([O-])(OCC[N+](C)(C)C)=O

Molecular Formula

C23H48NO4P

Molecular Weight

433.61

References & Citations

[1]Dawson R, et al. Phase I Single Ascending Dose and Food Effect Study in Healthy Adults and Phase I/IIa Multiple Ascending Dose Study in Patients with Pulmonary Tuberculosis to Assess Pharmacokinetics, Bactericidal Activity, Tolerability, and Safety of OPC-167832. Antimicrob Agents Chemother. 2023 Jun 15;67 (6) :e0147722. |[2]Paulussen C, et al. Efficacy of oleylphosphocholine (OlPC) in vitro and in a mouse model of invasive aspergillosis. Mycoses. 2015 Mar;58 (3) :127-32.