SKI-73
SKI-73 is a chemical probe for CARM1 with prodrug properties. SKI-73 can rapidly penetrate cell membranes and be processed into active inhibitors. SKI-73 inhibits the invasion of breast cancer cells and can be used in the study of cancer[1].
Product Specifications
CAS Number
[2206744-61-6]
UNSPSC
12352005
Target
Histone Methyltransferase
Related Pathways
Epigenetics
Field of Research
Cancer
Smiles
O[C@H]1[C@@H](O)[C@H](N2C(N=CN=C3N)=C3N=C2)O[C@@H]1C[C@@H](CNCC4=CC=CC=C4)CC[C@@H](C(NCCC5=CC=C(OC)C=C5)=O)NC(CC(C)(C)C6=C(C)C(C(C)=C(C)C6=O)=O)=O
Molecular Formula
C46H58N8O8
Molecular Weight
851.00
References & Citations
[1]Cai XC, et al. A chemical probe of CARM1 alters epigenetic plasticity against breast cancer cell invasion. Elife. 2019 Oct 28;8:e47110.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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