D-Val-Leu-Arg-pNA (hydrochloride)

D-Val-Leu-Arg-pNA hydrochloride is a substrate for glandular kinin-releasing enzymes. D-Val-Leu-Arg-pNA hydrochloride can be used to determine the activities of plasminogen activator and plasmin. D-Val-Leu-Arg-pNA hydrochloride is also used to study the fibrinolytic activity of various organisms, such as bacteria and worms[1][2].

Product Specifications

CAS Number

[1262750-87-7]

UNSPSC

12352005

Hazard Statement

H302-H315-H319

Target

PAI-1

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Others

Smiles

O=C([C@@H](NC([C@H](CC(C)C)NC([C@H](N)C(C)C)=O)=O)CCCNC(N)=N)NC1=CC=C([N+]([O-])=O)C=C1.Cl

Molecular Formula

C23H39ClN8O5

Molecular Weight

543.06

Precautions

P264-P270-P280-P302+P352-P330-P362+P364-P501

References & Citations

[1]Fischer BE, et al. Effects of intact fibrin and partially plasmin-degraded fibrin on kinetic properties of one-chain tissue-type plasminogen activator. Biochim Biophys Acta. 1990 Oct 18;1041 (1) :48-54.|[2]Kotb E, et al. A putative cytotoxic serine protease from Salmonella typhimurium UcB5 recovered from undercooked burger. Sci Rep. 2023 Mar 9;13 (1) :3926.