Patamostat (Standard)
Patamostat (Standard) is the analytical standard of Patamostat. This product is intended for research and analytical applications. Patamostat (E-3123) is a potent protease inhibitor. Patamostat potently inhibits trypsin, plasmin and thrombin with IC50s of 39 nM, 950 nM and 1.9 μM, respectively. Patamostat may possess suppressing effects on pathogenesis and development of acute pancreatitis[1][2].
Product Specifications
CAS Number
114568-26-2
UNSPSC
12352100
Target
Reference Standards; Ser/Thr Protease
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Inflammation/Immunology
Smiles
O=C(OC1=CC=C(SCCN2C(CCC2=O)=O)C=C1)C3=CC=C(NC(N)=N)C=C3
Molecular Formula
C20H20N4O4S
Molecular Weight
412.46
References & Citations
[1]K Miyamoto, et al. [Effects of E-3123, a New Protease Inhibitor, on Several Protease Activities and on Experimental Acute Pancreatitis]. Nihon Yakurigaku Zasshi. 1988 May;91 (5) :285-93.|[2]T Hirano, et al. Protective Effect of a Cephalosporin, Shiomarin, Plus a New Potent Protease Inhibitor, E3123, on Rat Taurocholate-Induced Pancreatitis. J Gastroenterol Hepatol. Jan-Feb 1993;8 (1) :52-9.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
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