Nebracetam

Nebracetam (WEB 1881 FU) is an orally active M1 muscarinic receptor agonist. Nebracetam can induce an increase in intracellular Ca2+ concentration, with an EC50 value of 1.59 mM. Nebracetam exhibits neuroprotective activity and the ability to improve cognitive impairment. Nebracetam can be used in the research of neurological diseases such as Alzheimer's disease[1][2].

Product Specifications

CAS Number

[97205-34-0]

Product Name Alternative

WEB 1881 FU

UNSPSC

12352005

Hazard Statement

H315-H319-H320

Target

Calcium Channel; mAChR

Related Pathways

GPCR/G Protein; Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Smiles

O=C1N(CC2=CC=CC=C2)CC(CN)C1

Molecular Formula

C12H16N2O

Molecular Weight

204.27

Precautions

P264-P280-P302+P352-P305+P351+P338-P362

References & Citations

[1]Kitamura Y, et al. Effects of nebracetam (WEB 1881 FU), a novel nootropic, as a M1-muscarinic agonist. Jpn J Pharmacol. 1991 Jan;55 (1) :177-80.|[2]Iwasaki K, et al. Effect of nebracetam on the disruption of spatial cognition in rats. Jpn J Pharmacol. 1992 Feb;58 (2) :117-26.