(2- (β-Piperidinoethyl) -9-hydroxyellipticinium chloride

(2- (β-Piperidinoethyl) -9-hydroxyellipticinium chloride (compound 1AA) is a SETBP1 inhibitor that disrupts the interaction between SETBP1 and XPO1. (2- (β-Piperidinoethyl) -9-hydroxyellipticinium chloride inhibits colony formation, induces differentiation/cytotoxicity, and downregulates the transcription of Setbpl target genes. (2- (β-Piperidinoethyl) -9-hydroxyellipticinium chloride improves survival and reduces the spleen size of leukemic mice. (2- (β-Piperidinoethyl) -9-hydroxyellipticinium chloride can be used for myeloid neoplasms and solid tumors research[1].