ADN 138
ADN-138 is an aldose reductase inhibitor. ADN-138 reduces sorbitol levels in diabetic nerves and results in significant increases in MNCV and Na+, K+-ATPase in the nerves. ADN-138 can be used in the research of diabetic nerve complications[1].
Product Specifications
CAS Number
99434-90-9
UNSPSC
12352005
Target
Aldose Reductase; Endogenous Metabolite; Na+/K+ ATPase
Related Pathways
Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease
Field of Research
Metabolic Disease; Neurological Disease
Smiles
O=C(N1)C2(CC1=O)C3=C4N(CCOC4=CC(Cl)=C3)C2=O
Molecular Formula
C13H9ClN2O4
Molecular Weight
292.67
References & Citations
[1]Hirata Y, Okada K. Relation of Na+, K (+) -ATPase to delayed motor nerve conduction velocity: effect of aldose reductase inhibitor, ADN-138, on Na+, K (+) -ATPase activity. Metabolism. 1990 Jun;39 (6) :563-7.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
More Discoveries
Explore Other Products
Browse additional items from our catalog
040496-APC 200 µL
PRPS1L1, NT (PRPS1L1, PRPS3, PRPSL, Ribose-phosphate pyrophosphokinase 3, Phosphoribosyl pyrophosphate synthase 1-like 1, Phosphoribosyl pyrophosphate synthase III) (APC) discontinued
Sign In for Pricing
View Details MBS808691-01 0.1 mg
4-Hydroxy-2-hexenal Antibody, Clone 6F10: Alkaline Phosphatase
Sign In for Pricing
View Details MBS808691-02 5x 0.1 mg
4-Hydroxy-2-hexenal Antibody, Clone 6F10: Alkaline Phosphatase
Sign In for Pricing
View Details