S-8666
S-8666 is an orally active uricosuric antihypertensive diuretic. The S-8666 has both S- (-) - and R- (+) -isomers. The diuretic and sodium-excretion activities of it are entirely dominated by the S- (-) -isomer, while the R- (+) -isomer shows no significant activity. S-8666 relies on the organic acid transport system to be secreted through the proximal tubule. S-8666 exhibits a clear uric acid excretion-promoting activity and diuretic effect in various species (such as rats and chimpanzees) [1][2].
Product Specifications
CAS Number
103968-87-2
UNSPSC
12352005
Target
Endogenous Metabolite
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Metabolic Disease; Cardiovascular Disease
Smiles
O=C(C1OC2=C(C1)C=C(S(=O)(N(C)C)=O)C(Cl)=C2Cl)O
Molecular Formula
C11H11Cl2NO5S
Molecular Weight
340.18
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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