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Tildacerfont-d8

Tildacerfont-d8 (SPR001-d8) is a deuterium labeled Tildacerfont (HY-113603) . Tildacerfont is a potent and orally active corticotrophin-releasing factor type 1 (CRF1) receptort antagonis. Tildacerfont effectively reduces adrenocorticotropic hormone (ACTH) and adrenal androgen levels. Tildacerfont has favourable safety profile. Tildacerfont can be used for researching congenital adrenal hyperplasia[1].

Product Specifications

CAS Number

[2762751-36-8]

Product Name Alternative

SPR001-d8; LY2371712-d8

UNSPSC

12352005

Target

CRFR; Isotope-Labeled Compounds

Related Pathways

GPCR/G Protein; Others

Field of Research

Cancer

Purity

99.68

Solubility

DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

CC1=NN(C(C(CC)CC)=CC(C)=N2)C2=C1C3=C(Cl)N=C(N4C([2H])([2H])C([2H])([2H])OC([2H])([2H])C4([2H])[2H])S3

Molecular Formula

C20H18D8ClN5OS

Molecular Weight

428.02

References & Citations

[1]Prete A, et al. Clinical advances in the pharmacotherapy of congenital adrenal hyperplasia. Eur J Endocrinol. 2021;186 (1) :R1-R14. Published 2021 Nov 30.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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