3-Methylglutaric acid (Standard)
3-Methylglutaric acid (Standard) is the analytical standard of 3-Methylglutaric acid. This product is intended for research and analytical applications. 3-Methylglutaric acid is a non-selective inhibitor of mitochondrial function and Na+, K+-ATPase, with an inhibition rate of 30% on rat cortical synaptosomal Na+, K+-ATPase. 3-Methylglutaric acid can induce reactive oxygen species (ROS) generation, thereby causing oxidative damage and inhibiting mitochondrial redox potential and ion pump function of cell membranes. 3-Methylglutaric acid can be used to study the neuropathological mechanisms of metabolic diseases and the role of oxidative stress-mediated neuronal damage in neurodegeneration[1][2][3][4].
Product Specifications
CAS Number
626-51-7
UNSPSC
12352211
Target
Mitochondrial Metabolism; Na+/K+ ATPase; Reactive Oxygen Species (ROS) ; Reference Standards
Related Pathways
Immunology/Inflammation; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; NF-κB; Others
Field of Research
Metabolic Disease; Neurological Disease
Smiles
O=C(O)CC(C)CC(O)=O
Molecular Formula
C6H10O4
Molecular Weight
146.14
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
Frequently Asked Questions
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