Taurolithocholic acid (sodium salt) (Standard)

Taurolithocholic acid (sodium salt) (Standard) is the analytical standard of Taurolithocholic acid (sodium salt) . This product is intended for research and analytical applications. Taurolithocholic acid sodium salt, a potent cholestatic agent, is a potent Ca2+ agonist[1].

Product Specifications

CAS Number

[6042-32-6]

UNSPSC

12352100

Target

Calcium Channel; Endogenous Metabolite; Reference Standards

Related Pathways

Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling; Others

Field of Research

Metabolic Disease

Smiles

C[C@@]12[C@](CC[C@]2([H])[C@H](C)CCC(NCCS(=O)(O[Na])=O)=O)([H])[C@@]3([H])[C@@](CC1)([H])[C@@]4([C@](C[C@@H](CC4)O)([H])CC3)C

Molecular Formula

C26H44NNaO5S

Molecular Weight

505.69

References & Citations

[1]U Beuers, et al. Modulation of protein kinase C by taurolithocholic acid in isolated rat hepatocytes. Hepatology. 1999 Feb;29 (2) :477-82.|[2]Ulrich Beuers, et al. Taurolithocholic acid exerts cholestatic effects via phosphatidylinositol 3-kinase-dependent mechanisms in perfused rat livers and rat hepatocyte couplets. J Biol Chem. 2003 May 16;278 (20) :17810-8.