FAPy-adenine (Standard)

FAPy-adenine (Standard) is the analytical standard of FAPy-adenine. This product is intended for research and analytical applications. FAPy-adenine is an oxidized DNA base. Fapy-adenine shows an increased trend levels in the Alzheimer's disease brain. Oxidized nucleosides are biochemical markers for tumors, aging, and neurodegenerative diseases[1][2][3].

Product Specifications

CAS Number

[5122-36-1]

UNSPSC

12352100

Target

Endogenous Metabolite; Reference Standards

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Cancer; Neurological Disease

Smiles

O=CNC1=C(N)N=CN=C1N

Molecular Formula

C5H7N5O

Molecular Weight

153.15

References & Citations

[1]Gabbita SP, et al. Increased nuclear DNA oxidation in the brain in Alzheimer's disease.|[2]Cysewski P, et al. Theoretical description of the coding potential of diamino-5-formamidopyrimidines. Z Naturforsch C J Biosci. 1999 Mar-Apr;54 (3-4) :239-45.|[3]Lee SH, et al. A rapid and sensitive method for quantitation of nucleosides in human urine using liquid chromatography/mass spectrometry with direct urine injection. Rapid Commun Mass Spectrom. 2004;18 (9) :973-7.