Allotetrahydrocortisol

Allotetrahydrocortisol (5a-Tetrahydrocortisol) is a metabolite of Cortisol. Cortisol is the main glucocorticoid in human. It is produced in adrenal cortex and plays a crucial role in many physiological processes[1][2].

Product Specifications

CAS Number

[302-91-0]

Product Name Alternative

5a-Tetrahydrocortisol

UNSPSC

12352211

Hazard Statement

H317, H413

Target

Endogenous Metabolite

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Others

Purity

99.53

Solubility

10 mM in DMSO

Smiles

C[C@@]12[C@](C(CO)=O)(O)CC[C@@]1([H])[C@]3([H])CC[C@@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])[C@@H](O)C2

Molecular Formula

C21H34O5

Molecular Weight

366.49

Precautions

H317, H413

References & Citations

[1]BUSH IE, et al. The excretion of allo tetrahydrocortisol in human urine. Biochem J. 1957 Dec;67 (4) :689-700.|[2]Kosicka K, et al. Detailed analysis of cortisol, cortisone and their tetrahydro- and allo-tetrahydrometabolites in human urine by LC-MS/MS. J Pharm Biomed Anal. 2017 Jun 5;140:174-181.