3-Hydroxyisobutyric acid (Standard)
3-Hydroxyisobutyric acid (Standard) is the analytical standard of 3-Hydroxyisobutyric acid. This product is intended for research and analytical applications. 3-Hydroxyisobutyric acid is an important interorgan metabolite, an intermediate in the pathways of l-valine and thymine and a good gluconeogenic substrate.
Product Specifications
CAS Number
2068-83-9
UNSPSC
12352100
Target
ATP Synthase; Endogenous Metabolite; Reference Standards
Related Pathways
Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Others
Field of Research
Metabolic Disease; Neurological Disease
Smiles
O=C(O)C(C)CO
Molecular Formula
C4H8O3
Molecular Weight
104.10
References & Citations
[1]Podebrad F, et al. Stereodifferentiation of 3-hydroxyisobutyric- and 3-aminoisobutyric acid in human urine by enantioselective multidimensional capillary gas chromatography-mass spectrometry. Clin Chim Acta. 2000 Feb 25;292 (1-2) :93-105.|[2]Viegas CM, et al. Evidence that 3-hydroxyisobutyric acid inhibits key enzymes of energy metabolism in cerebral cortex of young rats. Int J Dev Neurosci. 2008 May-Jun;26 (3-4) :293-9.|[3]Mardinoglu A, et al. Elevated Plasma Levels of 3-Hydroxyisobutyric Acid Are Associated With Incident Type 2 Diabetes. EBioMedicine. 2018 Jan;27:151-155.|[4]Landaas S. Accumulation of 3-hydroxyisobutyric acid, 2-methyl-3-hydroxybutyric acid and 3-hydroxyisovaleric acid in ketoacidosis. Clin Chim Acta. 1975 Oct 15;64 (2) :143-54.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
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