5-Methyltetrahydrofolic acid-13C5

5-Methyltetrahydrofolic acid-13C5 is the 13C-labeled 5-Methyltetrahydrofolic acid. 5-Methyltetrahydrofolic acid (5-Methyl THF) is a biologically active form of folic acid. 5-Methyltetrahydrofolic acid is a methylated derivate of tetrahydrofolate. 5-Methyltetrahydrofolic acid is the predominant natural dietary folate and the principal form of folate in plasma and cerebrospinal fluid[1].

Product Specifications

Product Name Alternative

5-Methyl THF-13C5; 5-MTHF-13C5

UNSPSC

12352005

Target

Endogenous Metabolite

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Metabolic Disease

Purity

98.0

Solubility

10 mM in DMSO

Smiles

CN1C2=C(NCC1CNC3=CC=C(C(N[13C@@H]([13CH2][13CH2][13C](O)=O)[13C](O)=O)=O)C=C3)NC(N)=NC2=O

Molecular Formula

C15 13C5H25N7O6

Molecular Weight

464.42

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Wright AJ, et al. Comparison of (6 S) -5-methyltetrahydrofolic acid v. folic acid as the reference folate in longer-term human dietary intervention studies assessing the relative bioavailability of natural food folates: comparative changes in folate status following a 16-week placebo-controlled study in healthy adults. Br J Nutr. 2010 Mar;103 (5) :724-9.