DMG-PEG 2000 (GMP Like)

DMG-PEG 2000 (GMP Like) is DMG-PEG 2000 (HY-112764) produced by using GMP like guidelines. GMP Like small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. DMG-PEG 2000 is used for the preparation of liposome for siRNA delivery with improved transfection efficiency in vitro. DMG-PEG 2000 is also used for the lipid nanoparticle for an oral plasmid DNA delivery approach in vivo through a facile surface modification to improve the mucus permeability and delivery efficiency of the nanoparticles[1].

Product Specifications

CAS Number

[160743-62-4]

UNSPSC

12352211

Hazard Statement

H302-H315-H319-H335

Target

Liposome

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Metabolic Disease

Smiles

CCCCCCCCCCCCCC(OC(COCCOC)COC(CCCCCCCCCCCCC)=O)=O.[n]

Molecular Formula

(C2H4O) nC32H62O5

Molecular Weight

2000 (Average)

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Tianqi Nie, et al. Surface Coating Approach to Overcome Mucosal Entrapment of DNA Nanoparticles for Oral Gene Delivery of Glucagon-like Peptide 1.ACS Appl Mater Interfaces. 2019 Aug 21;11 (33) :29593-29603.