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DOTAP (chloride) (GMP Like)

DOTAP chloride (GMP Like) is the GMP Like class DOTAP chloride (HY-112754A) . GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. DOTAP chloride is a cationic lipid with good membrane fusion ability and biocompatibility. DOTAP chloride (GMP Like) can be used as an excipient for transient and stable transfection DNA (plasmids, bacmids) and modified nucleic acids (antisense oligonucleotides) without the use of helper lipid[1].

Product Specifications

CAS Number

[132172-61-3]

Product Name Alternative

1,2-Dioleoyl-3-trimethylammonium-propane (chloride) (GMP Like)

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Liposome

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Others

Smiles

CCCCCCCC/C=C\CCCCCCCC(OCC(OC(CCCCCCC/C=C\CCCCCCCC)=O)C[N+](C)(C)C)=O.[Cl-]

Molecular Formula

C42H80ClNO4

Molecular Weight

698.54

Precautions

H302, H315, H319, H335

References & Citations

[1]Kim BK, et al. DOTAP/DOPE ratio and cell type determine transfection efficiency with DOTAP-liposomes.Biochim Biophys Acta. 2015 Oct;1848 (10 Pt A) :1996-2001.

Shipping Conditions

Blue Ice

Storage Conditions

Kept at -20 ± 5°C under an inert atmosphere.

Scientific Category

GMP Small Molecules

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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