5-Chloro-2'-deoxyuridine (Standard)

5-Chloro-2'-deoxyuridine (Standard) is the analytical standard of 5-Chloro-2'-deoxyuridine. This product is intended for research and analytical applications. 5-Chloro-2'-deoxyuridine, a thymine analog, is to study the potential of hypochlorous acid damage to DNA and DNA precursors.

Product Specifications

CAS Number

[50-90-8]

UNSPSC

12352100

Target

Nucleoside Antimetabolite/Analog; Reference Standards

Related Pathways

Cell Cycle/DNA Damage; Others

Field of Research

Neurological Disease

Smiles

OC[C@@H]1[C@@H](O)C[C@H](N2C(NC(C(Cl)=C2)=O)=O)O1

Molecular Formula

C9H11ClN2O5

Molecular Weight

262.65

References & Citations

[1]Kim CH, et al. Polymerase incorporation and miscoding properties of 5-chlorouracil. Chem Res Toxicol. 2010 Apr 19;23 (4) :740-8.|[2]Yuan CJ, et al. Extended access methamphetamine decreases immature neurons in the hippocampus which results from loss and altered development of neural progenitors without altered dynamics of the S-phase of the cell cycle. Pharmacol Biochem Behav. 2011 Nov;100 (1) :98-108.