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N1-Methylpseudouridine-5′-triphosphate (GMP like)

N1-Methylpseudouridine-5′-triphosphate (GMP like) (1-Methylpseudouridine-5′-triphosphate (GMP like) ) is N1-Methylpseudouridine-5′-triphosphate produced by using GMP like guidelines. GMP Like small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. N1-Methylpseudouridine-5′-triphosphate (1-Methylpseudouridine-5′-triphosphate) is a nucleobase-modified nucleotide, used for synthesizing mRNA with reduced immunogenicity and improved stability.

Product Specifications

CAS Number

1428903-59-6

Product Name Alternative

1-Methylpseudouridine-5′-triphosphate (GMP like)

UNSPSC

12352005

Target

DNA/RNA Synthesis; Nucleoside Antimetabolite/Analog

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Others

Smiles

O[C@H]1[C@@H](O)[C@H](C(C(N2)=O)=CN(C)C2=O)O[C@@H]1COP(OP(OP(O)(O)=O)(O)=O)(O)=O

Molecular Formula

C10H17N2O15P3

Molecular Weight

498.17

References & Citations

[1]Andries O, Mc Cafferty S, De Smedt SC, Weiss R, Sanders NN, Kitada T. N (1) -methylpseudouridine-incorporated mRNA outperforms pseudouridine-incorporated mRNA by providing enhanced protein expression and reduced immunogenicity in mammalian cell lines and mice. J Control Release. 2015;217:337-344.

Shipping Conditions

Room temperature

Scientific Category

GMP Small Molecules

Clinical Information

No Development Reported

Frequently Asked Questions

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