Betanin

Betanin has potent antioxidant and anti-inflammatory effect, that could inhibit peroxynitrite (ONOO-), with an IC50 of 19.2 μM. Betanin is a red glycoside obtained from beets that can be used as colorant.

Product Specifications

CAS Number

[7659-95-2]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Others

Related Pathways

Others

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease; Inflammation/Immunology

Purity

95.42

Solubility

H2O : 150 mg/mL (ultrasonic)

Smiles

O[C@H]1[C@H](OC2=CC(C[C@H]3C(O)=O)=C(C=C2O)N3/C=C/C(C4)=CC(C(O)=O)=N[C@@H]4C(O)=O)O[C@H](CO)[C@@H](O)[C@@H]1O

Molecular Formula

C24H26N2O13

Molecular Weight

550.47

Precautions

H302, H315, H319, H335

References & Citations

[1]Sakihama Y, et al. Beetroot betalain inhibits peroxynitrite-mediated tyrosine nitration and DNA strand cleavage. Free Radic Res. 2012 Jan;46 (1) :93-9.|[2]Sutariya B, et al. Betanin, isolated from fruits of Opuntia elatior Mill attenuates renal fibrosis in diabetic rats through regulating oxidative stress and TGF-β pathway. J Ethnopharmacol. 2017 Feb 23;198:432-443.|[3]Indumathi D, et al. Betanin exhibits significant potential as an antihyperglycemic and attenuating the glycoprotein components in streptozotocin-nicotinamide-induced experimental rats. Toxicol Mech Methods. 2018 Sep;28 (7) :547-554.