D-Lin-MC3-DMA (GMP Like)
D-Lin-MC3-DMA (GMP Like) is the GMP Like class D-Lin-MC3-DMA. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. D-Lin-MC3-DMA, an ionizable cationic lipid, is a potent siRNA delivery vehicle.
Product Specifications
CAS Number
1224606-06-7
UNSPSC
12352211
Hazard Statement
H302-H315-H319-H335
Target
Liposome
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer
Smiles
O=C(OC(CCCCCCCC/C=C\C/C=C\CCCCC)CCCCCCCC/C=C\C/C=C\CCCCC)CCCN(C)C
Molecular Formula
C43H79NO2
Molecular Weight
642.09
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Kulkarni JA, et al. Design of lipid nanoparticles for in vitro and in vivo delivery of plasmid DNA. Nanomedicine. 2017 May;13 (4) :1377-1387.|[2]Ferraresso F, Strilchuk AW, Juang LJ, Poole LG, Luyendyk JP, Kastrup CJ. Comparison of DLin-MC3-DMA and ALC-0315 for siRNA Delivery to Hepatocytes and Hepatic Stellate Cells. Mol Pharm. 2022;19 (7) :2175-2182.
Shipping Conditions
Room temperature
Scientific Category
GMP Small Molecules
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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