DOPE (GMP Like)
DOPE (GMP Like) is the GMP Like class DOPE , and can be used as pharmaceutical excipients. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. DOPE is a neutral helper lipid for cationic liposome and combines with cationic phospholipids to improve transfection efficiency of naked siRNA[1].
Product Specifications
CAS Number
4004-05-1
Product Name Alternative
Dioleoylphosphatidylethanolamine (GMP Like) ; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine (GMP Like)
UNSPSC
12352211
Target
Endogenous Metabolite; Liposome
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Smiles
O=P(OC[C@H](OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O)(OCCN)O
Molecular Formula
C41H78NO8P
Molecular Weight
744.03
References & Citations
[1]Uemura Y, et al. The efficiency of lipid nanoparticles with an original cationic lipid as a siRNA delivery system for macrophages and dendritic cells.Pharm Dev Technol. 2019 Mar;24 (3) :263-268.
Shipping Conditions
Room temperature
Scientific Category
GMP Small Molecules
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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