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DOPE (GMP Like)

DOPE (GMP Like) is the GMP Like class DOPE , and can be used as pharmaceutical excipients. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. DOPE is a neutral helper lipid for cationic liposome and combines with cationic phospholipids to improve transfection efficiency of naked siRNA[1].

Product Specifications

CAS Number

4004-05-1

Product Name Alternative

Dioleoylphosphatidylethanolamine (GMP Like) ; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine (GMP Like)

UNSPSC

12352211

Target

Endogenous Metabolite; Liposome

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Smiles

O=P(OC[C@H](OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O)(OCCN)O

Molecular Formula

C41H78NO8P

Molecular Weight

744.03

References & Citations

[1]Uemura Y, et al. The efficiency of lipid nanoparticles with an original cationic lipid as a siRNA delivery system for macrophages and dendritic cells.Pharm Dev Technol. 2019 Mar;24 (3) :263-268.

Shipping Conditions

Room temperature

Scientific Category

GMP Small Molecules

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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