S-1-Propenyl-L-cysteine (Standard)

S-1-Propenyl-L-cysteine (Standard) is the analytical standard of S-1-Propenyl-L-cysteine. This product is intended for research and analytical applications. S-1-Propenyl-L-cysteine is a stereoisomer of S-allyl-l-cysteine, extracted from garlic, with immunomodulatory effects and reduces blood pressure in a hypertensive animal model[1]. S-1-Propenyl-L-cysteine exhibits antioxidative efficacy through a NO-dependent BACH1 signaling pathway[2]. S-1-Propenyl-L-cysteine is orally active.

Product Specifications

CAS Number

[52438-09-2]

UNSPSC

12352100

Target

Histamine Receptor; Reference Standards

Related Pathways

GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling; Others

Field of Research

Metabolic Disease; Inflammation/Immunology; Cardiovascular Disease; Others

Smiles

N[C@@H](CS/C=C/C)C(O)=O

Molecular Formula

C6H11NO2S

Molecular Weight

161.23

References & Citations

[1]Kodera Y, et al. Chemical and Biological Properties of S-1-Propenyl-l-Cysteine in Aged Garlic Extract. Molecules. 2017 Mar 31;22 (4) .|[2]Tsuneyoshi T, et al., S-1-Propenylcysteine augments BACH1 degradation and heme oxygenase 1 expression in a nitric oxide-dependent manner in endothelial cells. Nitric Oxide. 2019 Mar 1;84:22-29.|[3]Matsutomo T, et al., Metabolomic study reveals the acute hypotensive effect of S-1-propenylcysteine accompanied by alteration of the plasma histidine level in spontaneously hypertensive rats. J Pharm Biomed Anal. 2019 May 10;168:148-154.|[4]Suzuki JI, et al., Anti-inflammatory action of cysteine derivative S-1-propenylcysteine by inducing MyD88 degradation. Sci Rep. 2018 Sep 20;8 (1) :14148.