P-Cresyl sulfate (Standard)

Platycodin D (Standard) is the analytical standard of Platycodin D. This product is intended for research and analytical applications. Platycodin D is a saponin isolated from Platycodon grandiflorus, acts as an activator of AMPKα, with anti-obesity property. WNT/β-catenin pathway mediates the anti-adipogenic effect of platycodin D[1][2].

Product Specifications

CAS Number

[3233-58-7]

Product Name Alternative

P-Tolyl sulfate (Standard)

UNSPSC

12352005

Target

JNK; p38 MAPK; Reactive Oxygen Species (ROS) ; Reference Standards

Related Pathways

Immunology/Inflammation; MAPK/ERK Pathway; Metabolic Enzyme/Protease; NF-κB; Others

Field of Research

Metabolic Disease

Smiles

O=S(OC1=CC=C(C)C=C1)(O)=O

Molecular Formula

C7H8O4S

Molecular Weight

188.20

References & Citations

[1]Wu TK, et al. The uremic toxin p-cresyl sulfate induces proliferation and migration of clear cell renal cell carcinoma via microRNA-21/ HIF-1α axis signals. Sci Rep. 2019 Mar 1;9 (1) :3207.|[2]Koppe L, et al. p-Cresyl sulfate promotes insulin resistance associated with CKD. J Am Soc Nephrol. 2013 Jan;24 (1) :88-99.|[3]Tanaka H, et al. p-Cresyl sulfate induces osteoblast dysfunction through activating JNK and p38 MAPK pathways. Bone. 2013 Oct;56 (2) :347-54.