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BB-Cl-Amidine (TFA)

BB-Cl-Amidine TFA is a peptidylarginine deminase (PAD) inhibitor[1].

Product Specifications

UNSPSC

12352005

Target

Protein Arginine Deiminase

Related Pathways

Epigenetics

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Smiles

O=C(C1=CC=C(C2=CC=CC=C2)C=C1)N[C@H](C3=NC4=C(N3)C=CC=C4)CCCNC(CCl)=N.OC(C(F)(F)F)=O

Molecular Formula

C28H27ClF3N5O3

Molecular Weight

573.99

References & Citations

[1]Knight JS, et al. Peptidylarginine deiminase inhibition disrupts NET formation and protects against kidney, skin and vascular disease in lupus-prone MRL/lpr mice. Ann Rheum Dis. 2015 Dec;74 (12) :2199-206.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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