NVC-422

NVC-422 is a N-chlorotaurine analog, virucidal agent, antibacterial agent. NVC-422 exhibits virucidal activity against Ad5 by the oxidative inactivation of key viral proteins (fiber and hexon), leading to the loss of viral integrity and infectivity. NVC-422 is shown to be highly effective in killing all microbial strains tested, including antibiotic-resistant S. aureus and E. faecium. NVC-422 can be used in the research of adenoviral conjunctivitis[1][2].

Product Specifications

CAS Number

[846056-87-9]

UNSPSC

12352211

Target

Bacterial; Drug Derivative

Related Pathways

Anti-infection; Others

Field of Research

Infection

Smiles

CC(C)(N(Cl)Cl)CS(=O)(O)=O

Molecular Formula

C4H9Cl2NO3S

Molecular Weight

222.09

References & Citations

[1]Yoon J, et al. Virucidal mechanism of action of NVC-422, a novel antimicrobial drug for the treatment of adenoviral conjunctivitis. Antiviral Res. 2011 Dec;92 (3) :470-8.|[2]Wang L, et al. Chemical characterization and biological properties of NVC-422, a novel, stable N-chlorotaurine analog. Antimicrob Agents Chemother. 2011 Jun;55 (6) :2688-92.