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ASP4000 (hydrochloride)

ASP4000 hydrochloride is a potent, competitive, selective, orally active DPP4 inhibitor with an IC50 value of 2.25 nM against human recombinant DPP4. ASP4000 hydrochloride shows antihyperglycemic activity. ASP4000 hydrochloride can be used in the research of type 2 diabetes[1].

Product Specifications

CAS Number

851389-35-0

UNSPSC

12352005

Target

Dipeptidyl Peptidase

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Metabolic Disease

Smiles

O=C([C@@H]1[C@H]2C[C@H]([C@H](O)C2)N1)N3[C@@H](CCC3)C#N.Cl

Molecular Formula

C12H18ClN3O2

Molecular Weight

271.74

References & Citations

[1]Tanaka-Amino K, et al. ASP4,000, a novel, selective, dipeptidyl peptidase 4 inhibitor with antihyperglycemic activity. Eur J Pharmacol. 2008 Aug 20;590 (1-3) :444-9.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

DPP-4

Frequently Asked Questions

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