UNBS3157
UNBS3157 is a naphthalimide derivative that shows potent anticancer effect. UNBS3157 induces autophagy and senescence in cancer cells. UNBS3157 displays significant antitumor effects in vivo. UNBS3157 can be used for leukemia, mammary adenocarcinoma, non-small cell lung cancer (NSCLC) and pancreatic cancer research[1].
Product Specifications
CAS Number
868962-26-9
UNSPSC
12352005
Target
Autophagy
Related Pathways
Autophagy
Field of Research
Cancer
Smiles
O=C(NC(NC1=CC2=CC=CC(C(N(CCN(C)C)C3=O)=O)=C2C3=C1)=O)C(Cl)(Cl)Cl
Molecular Formula
C19H17Cl3N4O4
Molecular Weight
471.72
References & Citations
[1]Van Quaquebeke E, et al. 2,2,2-Trichloro-N- ({2-[2- (dimethylamino) ethyl]-1,3-dioxo-2,3-dihydro-1H-benzo[de]isoquinolin- 5-yl}carbamoyl) acetamide (UNBS3157), a novel nonhematotoxic naphthalimide derivative with potent antitumor activity. J Med Chem. 2007 Aug 23;50 (17) :4122-34.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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