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A-850002

A-850002 is a metabotropic glutamate receptor (mGluR) antagonist (IC50=27 nM) that significantly attenuates spontaneous pain behavior after skin incision in rats. A-850002 can be used for analgesia research[1].

Product Specifications

CAS Number

869802-73-3

UNSPSC

12352005

Target

MGluR

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Neurological Disease

Smiles

O=C1C2=C(C3=C(C=NC=C3N(C)C)S2)N=CN1C4=CC=C(C)C=C4

Molecular Formula

C18H16N4OS

Molecular Weight

336.41

References & Citations

[1]Chang Z Zhu, et al. Analgesic activity of metabotropic glutamate receptor 1 antagonists on spontaneous post-operative pain in rats. European journal of pharmacology 580.3 (2008) : 314-321.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

MGluR1

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