A-850002
A-850002 is a metabotropic glutamate receptor (mGluR) antagonist (IC50=27 nM) that significantly attenuates spontaneous pain behavior after skin incision in rats. A-850002 can be used for analgesia research[1].
Product Specifications
CAS Number
[869802-73-3]
UNSPSC
12352005
Target
MGluR
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Smiles
O=C1C2=C(C3=C(C=NC=C3N(C)C)S2)N=CN1C4=CC=C(C)C=C4
Molecular Formula
C18H16N4OS
Molecular Weight
336.41
References & Citations
[1]Chang Z Zhu, et al. Analgesic activity of metabotropic glutamate receptor 1 antagonists on spontaneous post-operative pain in rats. European journal of pharmacology 580.3 (2008) : 314-321.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MGluR1
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