VA-111913
VA-111913 (VT-913) is a vasopressin receptor V1A antagonist (Ki = 1.74 nM) . VA-111913 reduces uterine contractions and improves uterine blood flow by inhibiting vasopressin, thereby alleviating dysmenorrhea. VA-111913 can be used for research on menstrual pain[1].
Product Specifications
CAS Number
877856-17-2
Product Name Alternative
VT-913
UNSPSC
12352005
Target
Vasopressin Receptor
Related Pathways
GPCR/G Protein
Field of Research
Neurological Disease; Cardiovascular Disease
Smiles
O=C(C1CC1)NCC2=CC=C(C(N3CC4=C(N(C)N=C4)NC5=CC(Cl)=CC=C35)=O)C=C2F
Molecular Formula
C23H21ClFN5O2
Molecular Weight
453.90
References & Citations
[1]Cole P, et al. Medicinal chemistry Highlights from the 239th American Chemical Society National Meeting & Exposition. Drugs of the Future. 2010;35 (6) :503-15.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
V1a Receptor
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