CGP52608
CGP52608 is a selective agonist for the RZR/ROR receptor, known for its anti-tumor activity, and has almost no affinity for the cell surface G-protein coupled melatonin receptor. CGP52608 can inhibit the growth of mouse 16/C breast cancer cells. CGP52608 can induce the formation of vesicles in diatoms[1][2].
Product Specifications
CAS Number
87958-67-6
UNSPSC
12352005
Target
Melatonin Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Cancer
Smiles
C=CCN1/C(SCC1=O)=N\NC(NC)=S
Molecular Formula
C8H12N4OS2
Molecular Weight
244.34
References & Citations
[1]S T Tslm, et al. CGP 52608-induced cyst formation in dinoflagellates: possible involvement of a nuclear receptor for melatonin. J Pineal Res. 1996 Sep;21 (2) :101-7.|[2]Katarzyna Winczyk, et al. Growth-inhibitory action of melatonin and thiazolidinedione derivative CGP 52608 on murine 16/C breast cancer cells. Neuro Endocrinol Lett. 2006 Jun;27 (3) :351-4.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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