Pyributicarb (Standard)
Proguanil (hydrochloride) (Standard) is the analytical standard of Proguanil (hydrochloride). This product is intended for research and analytical applications. Proguanil hydrochloride, an antimalarial proagent, is metabolized to the active metabolite Cycloguanil. Proguanil hydrochloride is a dihydrofolate reductase (DHFR) inhibitor[1][2].
Product Specifications
CAS Number
88678-67-5
Product Name Alternative
TSH-888 (Standard)
UNSPSC
12352005
Target
Cytochrome P450; Reference Standards
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Inflammation/Immunology
Smiles
S=C(OC1=CC=CC(C(C)(C)C)=C1)N(C2=NC(OC)=CC=C2)C
Molecular Formula
C18H22N2O2S
Molecular Weight
330.44
References & Citations
[1]Matsubara T, et al. Assessment of human pregnane X receptor involvement in pesticide-mediated activation of CYP3A4 gene. Drug Metab Dispos. 2007 May;35 (5) :728-33.|[2]Kojima H, et al. Comparative study of human and mouse pregnane X receptor agonistic activity in 200 pesticides using in vitro reporter gene assays. Toxicology. 2011 Feb 27;280 (3) :77-87.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
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