GTX-758

GTX-758 is an orally active, nonsteroidal, selective agonist of ERα. GTX-758 plays an important role in castration resistant prostate cancer (CRPC) research[1].

Product Specifications

CAS Number

[938067-78-8]

UNSPSC

12352005

Target

Estrogen Receptor/ERR

Related Pathways

Vitamin D Related/Nuclear Receptor

Field of Research

Cancer

Purity

99.59

Smiles

O=C(N(C1=CC=C(F)C=C1)C2=CC=C(O)C=C2)C3=CC=C(O)C(F)=C3

Molecular Formula

C19H13F2NO3

Molecular Weight

341.31

References & Citations

[1]M.S. Steiner, et al. 923P - GTX-758, An Oral ERa Agonist, Increases Sex Hormone Binding Globulin, Reduces Free T and Decreases PSA in Patients with Castration Resistant Prostate Cancer. Annals of Oncology Volume 23, Supplement 9, September 2012, Page ix304