GTX-758
GTX-758 is an orally active, nonsteroidal, selective agonist of ERα. GTX-758 plays an important role in castration resistant prostate cancer (CRPC) research[1].
Product Specifications
CAS Number
[938067-78-8]
UNSPSC
12352005
Target
Estrogen Receptor/ERR
Related Pathways
Vitamin D Related/Nuclear Receptor
Field of Research
Cancer
Purity
99.59
Smiles
O=C(N(C1=CC=C(F)C=C1)C2=CC=C(O)C=C2)C3=CC=C(O)C(F)=C3
Molecular Formula
C19H13F2NO3
Molecular Weight
341.31
References & Citations
[1]M.S. Steiner, et al. 923P - GTX-758, An Oral ERa Agonist, Increases Sex Hormone Binding Globulin, Reduces Free T and Decreases PSA in Patients with Castration Resistant Prostate Cancer. Annals of Oncology Volume 23, Supplement 9, September 2012, Page ix304
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
ERα
Available Sizes
Curated Selection
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