D-106669

D-106669 (comppun 150) is a potent inhibitor of PI3Kα, with the IC50 of 0.129 μM. D-106669 plays an important role in cancer research[1][2].

Product Specifications

CAS Number

[938444-93-0]

UNSPSC

12352005

Target

PI3K

Related Pathways

PI3K/Akt/mTOR

Field of Research

Cancer

Smiles

O=C(NC1=CC=C2C(N=C(NC3=CC=C(C)C=C3)C=N2)=N1)NCC

Molecular Formula

C17H18N6O

Molecular Weight

322.36

References & Citations

[1]Seipelt Irene, et al. Preparation of pyridopyrazines as kinase modulators. United States, US20070123494 A1 2007-05-31.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PI3Kα

Curated Selection

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