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CGP 31523A

CGP 31523A is a broad-spectrum aminothiazole cephalosporin. CGP 31523A exhibits potent inhibitory effects on Enterobacteriaceae, Neisseria, Haemophilus influenzae, and Streptococcus (except Enterococcus faecalis), among others. CGP 31523A can be hydrolyzed by the common Escherichia coli type Ic β-lactamase, but is stable against the Ia type enzyme. CGP 31523A is neither an effective β-lactamase inhibitor nor does it induce the production of β-lactamase. CGP 31523A can be used for studying infections caused by Gram-negative bacteria (including drug-resistant strains) [1].

Product Specifications

CAS Number

[94714-78-0]

UNSPSC

12352005

Target

Antibiotic; Bacterial

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

OC(C1=C(CSC2=CN=NS2)CS[C@@]([C@@H]3NC([C@H](C4=CSC(N)=N4)NC=O)=O)([H])N1C3=O)=O

Molecular Formula

C16H15N7O5S4

Molecular Weight

513.59

References & Citations

[1]Chin NX, Neu HC. Comparative in vitro activity and beta-lactamase stability of CGP 31523A, a new aminothiazolyl cephalosporin. Chemioterapia. 1986 Apr;5 (2) :92-100.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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