2,2,5,7,8-Pentamethyl-6-Chromanol (Standard)

2,2,5,7,8-Pentamethyl-6-Chromanol (Standard) is the analytical standard of 2,2,5,7,8-Pentamethyl-6-Chromanol. This product is intended for research and analytical applications. 2,2,5,7,8-Pentamethyl-6-Chromanol (PMC) is the anti-oxidant moiety of vitamin E (α-tocopherol) . 2,2,5,7,8-Pentamethyl-6-Chromanol has potent androgen receptor (AR) signaling modulation and anti-cancer activity against prostate cancer cell lines[1].

Product Specifications

CAS Number

[950-99-2]

Product Name Alternative

PMC (Standard)

UNSPSC

12352005

Target

Androgen Receptor; NF-κB; Reference Standards

Related Pathways

NF-κB; Others; Vitamin D Related/Nuclear Receptor

Field of Research

Cancer; Inflammation/Immunology; Cardiovascular Disease

Smiles

OC1=C(C)C(C)=C2C(CCC(C)(C)O2)=C1C

Molecular Formula

C14H20O2

Molecular Weight

220.31

References & Citations

[1]Kyriakopoulos CE, et al. A multicenter phase 1/2a dose-escalation study of the antioxidant moiety of vitamin E 2,2,5,7,8-pentamethyl-6-chromanol (APC-100) in men with advanced prostate cancer. Invest New Drugs. 2016 Apr;34 (2) :225-30.