CE-326597
CE-326597 is a small molecule agonist of the cholecystokinin A receptor (CCKAR) . CE-326597 occupies only the lower half of the TMD pocket and cannot mimic the crucial interaction between CCK-8 and ECL1-3. CE-326597 can be used to study metabolic diseases and gastrointestinal dysfunction[1].
Product Specifications
CAS Number
[870615-40-0]
UNSPSC
12352005
Target
Cholecystokinin Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Metabolic Disease
Smiles
O=C(N(C(C)C)CC1=CC=CC=C1)CN2C(C(CC3=CNC4=C3C=CC=C4)C5=NN=C(C6=CC=CC=C6)N5C7=CC=CC=C27)=O
Molecular Formula
C37H34N6O2
Molecular Weight
594.70
References & Citations
[1]Liu Q, et al. Ligand recognition and G-protein coupling selectivity of cholecystokinin A receptor. Nat Chem Biol. 2021 Dec;17 (12) :1238-1244.
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-11074/
Scientific Category
Reference compound1
Clinical Information
Phase 2
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