Cirsiliol (Standard)

Cirsiliol (Standard) is the analytical standard of Cirsiliol. This product is intended for research and analytical applications. Cirsiliol is a potent and selective 5-lipoxygenase inhibitor and a competitive low affinity benzodiazepine receptor ligand.

Product Specifications

CAS Number

[34334-69-5]

UNSPSC

12352100

Target

Lipoxygenase; Reference Standards

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Neurological Disease

Smiles

O=C1C=C(C2=CC=C(O)C(O)=C2)OC3=CC(OC)=C(OC)C(O)=C13

Molecular Formula

C17H14O7

Molecular Weight

330.29

References & Citations

[1]Mustafa EH, et al. Effects of cirsiliol, a flavone isolated from Achillea fragrantissima, on rat isolated ileum. Gen Pharmacol. 1992 May;23 (3) :555-60.|[2]Kang J, et al. Rhamnetin and cirsiliol induce radiosensitization and inhibition of epithelial-mesenchymal transition (EMT) by miR-34a-mediated suppression of Notch-1 expression in non-small cell lung cancer cell lines. J Biol Chem. 2013 Sep 20;288 (38) :27343-57.