MRS2905 (trisodium)
MRS2905 (α, β-Methylene-2-thio-UDP) trisodium is a selective P2Y14R agonist with an EC50 of 0.92 nM. MRS2905 trisodium is inactive at the UDP-activated P2Y6 receptor, and at other P2Y receptors[1].
Product Specifications
CAS Number
[3033550-04-5]
Product Name Alternative
A, β-Methylene-2-thio-UDP (trisodium)
UNSPSC
12352005
Target
P2Y Receptor
Related Pathways
GPCR/G Protein
Field of Research
Inflammation/Immunology
Smiles
O[C@@H]1[C@H](O)[C@@H](COP(CP(O[Na])(O[Na])=O)(O[Na])=O)O[C@H]1N(C(N2)=S)C=CC2=O
Molecular Formula
C10H13N2Na3O10P2S
Molecular Weight
484.20
References & Citations
[1]Lazarowski ER, et al. UDP-Sugars as Extracellular Signaling Molecules: Cellular and Physiologic Consequences of P2Y14 Receptor Activation. Mol Pharmacol. 2015 Jul;88 (1) :151-60.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
P2Y14 Receptor
Available Sizes
Curated Selection
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