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SM-350300

SM-350300 is a glucoprotein. SM-350300 stimulates lipolysis in white adipocytes by activating the cyclic AMP (cAMP) pathway, and upregulates the expression of lipolytic enzymes and uncoupling proteins (UCP1, UCP3) in brown adipose tissue (BAT) and white adipose tissue (WAT) . SM-350300 reduces body weight by decreasing carcass fat while increasing lean muscle mass in metabolic disorder models. SM-350300 can be used for the study of metabolic disorders including obesity, type 2 diabetes, and cachexia[1].

Product Specifications

CAS Number

[902750-48-5]

UNSPSC

12352005

Target

Others

Related Pathways

Others

Field of Research

Metabolic Disease

Smiles

C[C@H](OC1=CC=CC2=C1NC=C2CCNC[C@H](O)C3=CC=CN=C3)C(OCC)=O

Molecular Formula

C22H27N3O4

Molecular Weight

397.47

References & Citations

[1]Tisdale, M. J., et al. Glycoproteins Having Lipid Mobilizing Properties and Therapeutic Uses Thereof. International Patent No. WO 2011/161427 A2. World Intellectual Property Organization (WIPO) . Published on December 29, 2011.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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