SAR216471 (hydrochloride)

SAR216471 hydrochloride is a P2Y12 receptor antagonist. SAR216471 hydrochloride has antiplatelet and antithrombotic activities in vivo[1].

Product Specifications

CAS Number

[1279829-64-9]

UNSPSC

12352005

Target

P2Y Receptor

Related Pathways

GPCR/G Protein

Field of Research

Inflammation/Immunology

Smiles

O=C(C1=CN(CC(N2CCN(CC2)C)=O)C3=C1C=C(Cl)C=C3)NC4=NN=C(N5N=CC(C(CCC)=O)=C5C)C=C4.Cl

Molecular Formula

C28H32Cl2N8O3

Molecular Weight

599.51

References & Citations

[1]Boldron C, et al. N-[6- (4-butanoyl-5-methyl-1H-pyrazol-1-yl) pyridazin-3-yl]-5-chloro-1-[2- (4-methylpiperazin-1-yl) -2-oxoethyl]-1H-indole-3-carboxamide (SAR216471), a novel intravenous and oral, reversible, and directly acting P2Y12 antagonist. J Med Chem. 2014 Sep 11;57 (17) :7293-316.