AZD-2066 (hydrochloride)
AZD-2066 hydrochloride is a selective, orally active and blood-brain barrier-permeating mGluR5 antagonist. AZD 2066 hydrochloride activates the BDNF/trkB signaling pathway. AZD 2066 hydrochloride can be used in the research of neuropathic pain, major depressive disorder and gastroesophageal reflux disease[1][2][3][5].
Product Specifications
CAS Number
[934338-70-2]
UNSPSC
12352005
Target
Calcium Channel; mGluR; Trk Receptor
Related Pathways
GPCR/G Protein; Membrane Transporter/Ion Channel; Neuronal Signaling; Protein Tyrosine Kinase/RTK
Field of Research
Neurological Disease
Smiles
CN1C(C2=CC=NC=C2)=NN=C1O[C@@H](C3=NOC(C4=CC(Cl)=CC=C4)=C3)C.Cl
Molecular Formula
C19H17Cl2N5O2
Molecular Weight
418.28
References & Citations
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-110255B/
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
MGluR5
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