AZD 9272 (Standard)
AZD 9272 (Standard) is the analytical standard of AZD 9272. This product is intended for research and analytical applications. AZD 9272 is a brain penetrant mGluR5 antagonist.
Product Specifications
CAS Number
327056-26-8
UNSPSC
12352100
Target
MGluR; Reference Standards
Related Pathways
GPCR/G Protein; Neuronal Signaling; Others
Field of Research
Neurological Disease
Smiles
N#CC1=CC(F)=CC(C2=NC(C3=CC=C(F)C=N3)=NO2)=C1
Molecular Formula
C14H6F2N4O
Molecular Weight
284.22
References & Citations
[1]Swedberg MD, et al. AZD9272 and AZD2066: selective and highly central nervous system penetrant mGluR5 antagonists characterized by their discriminative effects. J Pharmacol Exp Ther. 2014 Aug;350 (2) :212-22.|[2]Raboisson P, et al. Discovery and characterization of AZD9272 and AZD6538-Two novel mGluR5 negative allosteric modulators selected for clinical development. Bioorg Med Chem Lett. 2012 Nov 15;22 (22) :6974-9.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
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